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DIOXYGENASE, TDO
Descriptors Found:
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DeCS
Descriptor
English
:
Tryptophan Oxygenase
Descriptor
Spanish
:
Triptófano Oxigenasa
Descriptor
Portuguese
:
Triptofano Oxigenase
Synonyms
English
:
TDO Dioxygenase
Tryptophan 2,3-Dioxygenase
2,3-Dioxygenase, Tryptophan
Dioxygenase, TDO
Oxygenase, Tryptophan
Pyrrolase, Tryptophan
Tryptophan 2,3 Dioxygenase
Tryptophan Pyrrolase
Tree Number:
D08.811.682.690.416.722
Definition
English
:
A dioxygenase with specificity for the
oxidation
of the indoleamine ring of
TRYPTOPHAN
. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the
kynurenine
pathway of
TRYPTOPHAN
catabolism.
See Related
English
:
Tryptophan Hydroxylase
History Note
English
:
68(65)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
14768
Unique Identifier:
D014366
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS